Primobolan Depot

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Primobolan Depot

DIN 00089986
200 mg/2mL, 1000 mg/10 mL
10 mL Multiple-Dose, Cartons of 1 vial

Systematic name: (5α,17β)-1-Methyl-3-oxoandrost-1-en-17-yl heptanoate

Availability: In stock

$0.00
Pharmacokinetic data

Drug Class: Anabolic/Androgenic Steroid

Androgenic Rating: 44-57

Anabolic Rating: 88

Route: intramuscular, (I.M)

Effective Dose: Men, 200-400 mg

Effective Dose: Women, 50-100 mg

Injection Required: 7-10 day

Half-Life: 10.5 day
Detection Time: 5 week

Excretion: Urine

Side Effects

Acne:  Yes, mainly in higher doses

Fluid retention: Low

Hypertension: Rare

Hepatotoxicity: Low

Aromatization: None

DHT Conversion: None

Decrease HPTA Function: Yes

Identifiers

CAS number : 303-42-4
PubChem CID: 248271

ChemSpiderID: 217360

Chemical data

Formula: C27H42O3
Mol. mass: 414.62058 g/mL

Melting point: 65C~ 71C

DESCRIPTION
Primobolan depot (Methenolone enanthate) is a dihydrotestosterone (DHT) based anabolic steroid. It is an ester derivative of methenolone. When it interacts with the aromatase enzyme, it does not form any estrogens. It is used by people who are very susceptible to estrogenic side effects, having lower estrogenic properties than Nandrolone. Methenolone enanthate is available as an injection formulation. The injection is regarded as having a higher bioavailability. It is an enanthate ester which is quite long-acting. Because it by-passes hepatic breakdown on the first pass, it also has a higher survival rate. Methenolone is not 17-alpha-alkylated, therefor it is less stressful on the liver. In doses
of 200 mg per week or less (intramuscular), blood pressure is rarely altered.

COMPOSITION
Medicinal ingredients and Non-Medicinal ingredients
Each 2mL contains: Methenolone enanthate, 200 mg; benzyl alcohol, 9 mg; cottonseed oil USP. q.s

PHARMACOLOGICAL CLASSIFICATION
A. 21.6 Anabolic steroids.

PHARMACOLOGICAL ACTION
In aplastic anaemia of various origins - both the idiopathic forms and those with exogenously damaged bone marrow - high doses of methenolone may stimulate bone marrow function, particularly erythropoiesis.

INDICATIONS
Aplastic anaemia.Aplastic anemia is a disease in which the bone marrow, and the blood stem cells that reside there are damaged. It causes a deficiency of all three blood cell types (pancytopenia): red blood cells (anemia), white blood cells (leukopenia) and platelets (thrombocytopenia).

CONTRAINDICATIONS
Primobolan Depot is contra-indicated in pregnancy as the Methenolone enanthate contained in the preparation, like all anabolic agents, possesses some androgenic activity which may lead to signs of virilization in the female newborn. Because of the androgenic activity, Primobolan Depot is also contra-indicated in patients with prostatic carcinoma, since such substances may aggravate the disease.

DOSAGE AND ADMINISTRATION
The therapy may have to be continued for at least 3 months at a dosage of 3-5 mg/kg bodyweight per week, 300-500 mg/week for a person weighing 100 kg. Since some patients only respond after several months, treatment must not be stopped too soon. After improvement of the clinical picture, treatment should, as a general rule, be continued for a further few weeks. Deterioration of the blood count after discontinuation of therapy may be reversed by renewed administration of Primobolan Depot.

WARNINGS AND PRECAUTIONS
In female patients, signs of virilization (acne, Hirsutism, hoarseness, possibly irreversible deepening of the voice) must be reckoned with. For sexually mature women, menstrual irregularities may occur. In adult males, spermatogenesis may be inhibited. In boys, there may be signs of premature puberty. Non-adult patients should be monitored for accelerated bone maturation by X-ray. In men, regular examinations of the prostate should be carried out prophylactically to exclude a malignant tumour. Methenolone can be suppressive of the hypothalamic-pituitary-Gonadal axis.

OVERDOSAGE AND PARTICULARS OF ITS TREATMENT
The symptoms mentioned under "Side effects and special precautions" may occur.
There is no specific antidote.

STORAGE
Vial should be kept away from light and stored in controlled temperature from 20-25 degree Celsius (68° TO 77°F)  Warming and shaking the vial should redissolve any crystals that may have formed during storage. Keep out of reach of children.

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